I have experienced three very different types of biocuration work in my career. My first taste of biocuration was in a research lab curating information about olfactory receptor genes. I then moved to work on the well-established functional genomics databases of ArrayExpress and the Expression Atlas at EMBL-EBI curating data submissions submissions. From there I moved to a project at the University of Dundee setting up the Image Data Resource for bioimaging data. This was my biggest curation challenge, starting almost from scratch to develop a method to capture the biomolecular, experimental and analytic annotations associated with images, and to create a pipeline to populate the database. I will describe the most useful biocuration skills I have learnt and some of the challenges I’ve encountered. I will finish by describing my new position, working as a scientific curator in a company performing analyses of the genomes of patients with rare diseases.